Etiology, treatment, and outcomes
Understanding the current science on gender dysphoria's causes, available treatments and outcomes, and live clinical controversies is essential to supporting families well. This page organizes relevant publications — separated by whether the transgender family member is a child/adolescent or an adult — alongside several current issues clinicians are likely to encounter.
A note on inclusion: listing a publication here doesn't imply endorsement by the Regeneration Resource Center. Few resources are written from an explicitly Christian perspective — the main exceptions are the Christian Medical & Dental Associations' transgender resources and Yarhouse (2015) below. Even where you may disagree with an author's underlying view of transgender identity, the information presented can still be useful.
Etiology (causes) of gender dysphoria
-
Gender Identity Disorder and Psychosexual Problems in Children and Adolescents — see chapters 6–7 on biological and psychosocial etiology. Though published in 1995, its summary of the research gaps largely still holds; Hruz (2020) offers some updates on biological etiology (pp. 35–36).
-
From Mental Disorder to Iatrogenic Hypogonadism — a balanced peer-reviewed discussion of the "pathologic condition vs. natural variation" debate (pp. 5–9), concluding that gender identity is likely best understood as a complex interaction of biological, individual, and environmental factors, without strong empirical support yet for any single model.
-
Lev, A. (2004). Transgender Emergence. New York: Routledge — see Ch. 4, Etiologies.
Treatments for gender dysphoria & outcomes
-
WPATH Standards of Care — useful for helping family members understand available treatment options.
-
Transgenderism and Intersexuality in Childhood & Adolescence — see chapters 6–7 on clinical management.
-
Advancing the Practice of Pediatric Psychology with Transgender Youth — current treatment options, useful for explaining these to families.
-
Adolescents with Gender Dysphoria — covers rising referral rates, the growing share of referred biological females, suicide risk, and rapid-onset presentations.
-
The Battle Over Gender Therapy (NYT) — summarizes current clinical debates.
-
They Paused Puberty, but Is There a Cost? (NYT) — tradeoffs of puberty blockers.
-
Brown, M. & Rounsley, C.A. (2003). True Selves. San Francisco: Jossey-Bass — secular perspective.
-
Yarhouse, M. (2015). Understanding Gender Dysphoria. Downers Grove, IL: InterVarsity Press — conservative Christian perspective; Ch. 5 covers treatment.
-
Yarhouse, M. & Sadusky, J. (2022). Gender Identity & Faith. Downers Grove, IL: InterVarsity Press — for clinicians helping clients reconcile faith and gender identity.
Interventions for families with a transgender child or adolescent
-
Brill, S.A. & Pepper, R. (2008). The Transgender Child. San Francisco: Cleis Press — Ch. 2, Family Acceptance: From Crisis to Empowerment.
-
Coolhart, D. & Shipman, D.L. (2017). Working Toward Family Attunement. Psychiatr Clin North Am, 40(1), 113–125 — secular family therapy model.
-
Ehrensaft, D. (2011). Gender Born, Gender Made. New York: Experiment — Ch. 2, The Family's Path Is Covered with Roses and Thorns.
-
Gottlieb, A.R. & Lev, A.I. (2019). Families in Transition. New York: Harrington Park Press — Ch. 5 on extended family, Ch. 11 on parents' identity, Ch. 17 on siblings.
-
Raj, R. (2008). Transforming Couples and Families. Journal of GLBT Family Studies, 4(2), 133–163 — the Trans-Formative Therapeutic Model, written by a transgender clinician.
-
SAMHSA (2014). A Practitioner's Resource Guide: Helping Families to Support Their LGBT Children. Available here.
-
Wahlig, J.L. (2015). Losing the Child They Thought They Had. Journal of GLBT Family Studies, 11(4), 305–326 — ambiguous loss perspective.
-
Additional secular resources: Cooper (2009); Golden & Oransky (2019); MacNish & Gold-Peifer (2014); Malpas (2011); Vanderburgh (2009).
Interventions for families with a transgender adult
-
Lev, A. (2004). Transgender Emergence, Ch. 8, Family Emergence — one of the earliest resources specifically addressing families with a transgender adult.
-
Raj (2008), above, also addresses the Trans-Formative Therapeutic Model as applied to families with a transgender adult.
Continue exploring: